See any site problems? Let us know if something looks wrong or isn't working. Click here Report a problem
Obesity is generally associated with a worse prostate cancer prognosis among men whose tumors contain TMPRSS2-ERG, a hormonally regulated gene fusion which leads to the over-expression of a truncated ERG protein, is present in about half of all prostate tumors. This is the conclusion reached by researchers from Harvard School of Public Health (HSPH), Dana-Farber Cancer Institute and Brigham and Women's Hospital researchers.
The study shows that…Continue
Colorectal cancer is the third leading cause of cancer-related death in the Western world. And although it is a highly treatable and often curable disease when localized to the bowel, surgery is still the primary form of treatment which results in a cure in approximately 50% of the patients. Recurrence following surgery is a major problem and is often the ultimate cause of death.
Based on recent estimates from the American Cancer Society, there will be 102,480 new cases and…Continue
According to new research published in the November 29, 2013 edition of Nature Communications, a protein called Cyclin D1 (G1/S-specific cyclin-D1 or CCND1) which helps push a replicating cell through the cell cycle also mediates the processing and generation of mature microRNA (miRNA).
The research suggests that Cyclin D1 which is strongly implicated in human cancer, also governs the non-protein-coding genome. The non-coding genome, previously referred to as junk…Continue
A new study published in the November 29, 2013 edition of the journal Science, sheds new light on a woman's risk of developing breast cancer. The study, for the first time, explains the reason behind the established relationship between high cholesterol and breast cancer -- especially in obese women who have reached menopause.
Researchers from Duke Cancer Institute in North Carolina found that a primary…Continue
Many patients around the globe do not have access to proper opioid analgesics - critical to the effective relief and management of cancer pain. This lack of access represent a serious public health problem. These conclusions are from the Global Opioid Policy Initiative (GOPI) project, a ground-breaking international collaborative survey which show that more than 4 billion people live in countries where regulations designed to to stem drug misuse, leave cancer patients suffering…Continue
According to results from a recent study published in the November 27, 2013 online edition of Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research, women who are members of families with BRCA2 mutations but who test negative for the family-specific BRCA2 mutations are still at greater risk for developing breast cancer compared with women in the general population.
Women with certain mutations in their BRCA1 or BRCA2…Continue