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The information contained in Onco'Zine - The International Cancer Network is generally technical in nature and intended for Healthcare Professionals.
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Researchers from the Okayama University in Japan report photoimmunotherapy to be effective against elusive gastric cancer cells following transduction with the gene that expresses the extracellular domain protein of HER2. The results are published in the February 2016 edition of the journal Small Molecule Therapeutics in February 2016.
“Gastric cancer is one of the most common malignancies worldwide, making it the third leading cause of cancer-related death,” explain…Continue
A new study supported by funding from the National Institutes of Health and the Yale Cancer Center sheds light on how melanoma cells change from benign to malignant, and how the complex interaction between the cells and their surrounding environment affects outcomes of the cancer.
The transition from the radial growth patterns of benign melanoma cells to the vertical patterns of malignant cells has long been a mystery to researchers. But a study from the lab of Andre Levchenko, the…Continue
Several drugs now being used to treat heart failure and atrial arrhythmia also show promise as DNA disruptors in cancer cells and could be readily repurposed as anticancer agents, according to a new study by Yale researchers which was supported by the National Institute of General Medical Sciences, CureSearch for Children’s Cancer, and the Yale Center for Molecular Discovery.
Cardiac glycosides, which are bioactive natural products found in certain plants and insects, aid in cardiac…Continue
Contributing Editors: Amit Kumar, Ph.D and Robert Berman
For nearly 45 years, the national dialogue, when it comes to cancers, has remained essentially the same. We have been racing for the cure, praying for the cure, searching for the cure, researching for the cure, raising money for the cure, funding the cure, and developing treatments for the cure. Curing cancer has become the “national cancer objective”.…Continue
Senior leaders from more than a dozen biopharmaceutical companies came together today with world-class academic clinicians from four leading cancer centers, representatives from oncology non-profits, the FDA, and other key stakeholder organizations to advance the most promising avenues for curing cancer: accelerating the development of investigational drug combination therapies of two or more investigational treatments which may hold great promise for cancer patients.
Located just behind the stomach, measuring about 6 inches long and less than 2 inches wide, is an organ called the pancreas. Shaped like a fish with a wide head, a tapering body and a small, pointed tail, the pancreas contains 2 different types of glands - exocrine and endocrine - which are a vital part of the digestive system and a critical controller of blood sugar levels.
Tumors of the pancreas are malignant neoplasms arising in the pancreas. Because of its 'hidden' location, these…Continue
By Sonia Portillo, Medical Writer
In the current oncology therapeutics market, an estimated $45 billion is brought in through cytogenic therapeutics. Of that amount, 70% is attributed to generic cytostatics, which are largely dominated by paclitaxel-based products Taxol and Abraxane® (Celgene). In fact, before going generic, Taxol brought in around 1.6 billion dollars annually, and it was used for 16 cancer indexes. Just last…Continue
Although the United States has curtailed the use of asbestos-containing products in residential and commercial construction, the effects of asbestos exposure are still a major concern. Additionally, there are several places around the world where asbestos exposure is still quite high. Asbestos occurs naturally in the ground in countries like Turkey.…Continue
Although based on early data, study findings suggest an association between the Affordable Care Act Dependent Coverage Expansion provision and cervical cancer stage at diagnosis and receipt of fertility-sparing treatment among young women age 21 to 25 years, but not among women aged 26 to 34 years, according to a study, supported by the Intramural Research Department of the American Cancer Society, published in the November 24 issue of JAMA.
In September 2010,…Continue
Biomedical engineers at Texas A&M University, committed to solving the world’s greatest health problems through the exploration of new ideas, integrated research and innovation, have developed a new technology focusing on a new synthetic material that’s strong enough to fill gaps in bone while stimulating new bone growth that could advance the grafting treatments needed by people suffering from bone cancer and other bone defects.
"This material serves as a biodegradable scaffold…Continue