February 2015 Blog Posts (2)

Study Associates Gene Variant With Increased Risk and Severity of Nerve Disorder Linked to Widely-Prescribed Cancer Drug

A study published in the February 24, 2015 issue of JAMA, the Journal of The American Medical Association, suggests that children with acute lymphoblastic leukemia who had a certain gene variant experienced a higher incidence and severity of peripheral neuropathy after receiving treatment with the cancer drug vincristine (Oncovin®/ Vincasar Pfs®).

Despite major advances over the last 2 decades, cancer remains the leading cause of death by disease in children in the United…

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Added by Peter Hofland, PhD on February 24, 2015 at 11:00am — No Comments

Researchers Identify Biomarkers and Combination Therapies that Hone Path to ONC201 Clinical Success

ONC201 is a small molecule inducer of the TRAIL gene under current investigation as a novel anticancer agent. The small molecule drug has a unique mechanism of action that causes significant anti-tumor activity in a variety of types of human cancer.



In an article published OnlineFirst on February 13, 2015 in Cancer Research, a journal published by the American Association for Cancer Research (AACR), Professor Wafik El-Deiry, MD, PhD, FACP, Co-Program Leader of Molecular…

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Added by Peter Hofland, PhD on February 20, 2015 at 1:00pm — No Comments

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