The U.S. Food and Drug Administration today approved crizotinib(Xalkori®, Pfizer), to treat certain patients with late-stage (locally advanced or metastatic), non-small cell lung cancers (NSCLC) who express the abnormal anaplastic lymphoma kinase (ALK) gene.



Crizotinib is being approved with a companion diagnostic test and is the second such targeted therapy approved by the FDA this…

Women at high risk of developing breast cancer who smoked cigarettes and drank alcohol were less likely to continue with their chemopreventive regimen and may require more adherence support, according to results of a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research.



“Our results might suggest there are common factors,…

African-American women are at higher risk for hormone receptor-negative breast cancer, one of the most difficult subtypes to treat, but this risk could be ameliorated somewhat by breast-feeding their children.



“African-American women are more likely to have had a greater number of full-term births and less likely to have breast-fed their babies,” said Julie Palmer, Sc.D., professor of epidemiology at the…

Childhood cancer survivors with poor physical health and neurocognitive deficits are more likely to be unemployed or work part-time in adulthood, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.



Research to date has indicated that while more children with cancer are surviving, the treatments received can…