September 2012 Blog Posts (9)

Drug Combinations Offer New Ways to Treat Metastatic Melanoma

Trials with drugs that target BRAF have generated excitement for their ability to quickly shrink melanoma tumors in suitable patients. But for many patients the benefits proved short-lived, as the cancer cells develop resistance to the drugs. New phase I and II trials focusing on combining drugs to slow the development of resistance to drugs that inhibit BRAF, a gene that is mutated in about half of melanomas presented at ESMO 2012, the…

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Added by Peter Hofland, PhD on September 29, 2012 at 8:07am — No Comments

Despite Decades of Research Pancreatic Cancer Remains Notoriously Difficult to Treat

A key driver behind the poor response seen with many chemotherapies and targeted agents evaluated in this setting is thought to be the stroma, which acts as a mechanical barrier to stop drug penetration and also hinder neovascularization, creating a hypoxic microenvironment. The study results of a clinical trial including TH-302, a novel anticancer agent that is converted to bromo-isophosphoramide mustard (Br-IPM), presented at ESMO 2012,…

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Added by Peter Hofland, PhD on September 29, 2012 at 7:00am — No Comments

First Ever Estimate Reveals the Direct and Indirect Economic Burden of Cancer in Europe

New studies that reveal for the first time the real economic and human costs of caring for cancer patients in Europe were presented during the ESMO 2012 Congress of the European Society for Medical Oncology in Vienna, Austria (September 28 - October 2, 2012).

“Here we have two studies of…

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Added by Peter Hofland, PhD on September 29, 2012 at 6:30am — No Comments

New Drug Application Submitted for Tivozanib for theTreatment of Advanced Renal Cell Carcinoma

Today AVEO Oncology announced that it has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) seeking approval for tivozanib in patients with advanced renal cell carcinoma (RCC).

Advanced RCC, or kidney cancer, is the ninth most commonly diagnosed cancer in men and women in the U.S.[1] Worldwide it is estimated that more than 250,000…

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Added by Peter Hofland, PhD on September 28, 2012 at 9:00am — No Comments

ESMO 2012 Congress: Urgent Need for Integrated Oncology and Palliative Care

ESMO, the European Society for Medical Oncology, has awarded "ESMO Designated Center of Integrated Oncology and Palliative Care" accreditation to 16 new oncology centers. As part of the accreditation, the centers will receive the acknowledgment at the ESMO 2012 Congress, in Vienna, Austria, 28…

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Added by Peter Hofland, PhD on September 24, 2012 at 12:30pm — No Comments

ESMO 2012 Congress: Urgent Need for Integrated Oncology and Palliative Care

ESMO, the European Society for Medical Oncology, has awarded "ESMO Designated Center of Integrated Oncology and Palliative Care" accreditation to 16 new oncology centers. As part of the accreditation, the centers will receive the acknowledgment at the ESMO 2012 Congress, in Vienna, Austria, 28…

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Added by Peter Hofland, PhD on September 24, 2012 at 12:30pm — No Comments

Cancer in the Movies: It’s Time Cinema Directors Realize Cancer isn’t Always a Death Sentence

Films that feature characters with cancer have become a familiar sight for movie-goers in recent years, but they rarely portray the patient’s chances of survival accurately. During the upcomming ESMO 2012 Congress of the European Society for Medical Oncology in Vienna, Austria, Italian researchers will present their finding about how cancer is portrayed in the movies. 

Movies often show an…

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Added by Peter Hofland, PhD on September 20, 2012 at 5:00pm — No Comments

Novel Device for Follow-Up Surgery After Lumpectomy: No Extra Tissue Needed

Results of a large prospective study on the treatment of early breast cancer presented during the 2012 Breast Cancer Symposium at the San Francisco Marriott Marquis in San Francisco, CA, September 13-15, 2012, determined that the use of a novel device called MarginProbe helps ensure that sufficient tissue is removed during a lumpectomy.  This results in fewer additional surgeries helping to avoid cost of having to remove larger amounts of tissue. For patients, this could…

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Added by Peter Hofland, PhD on September 13, 2012 at 11:30am — No Comments

Study Shows Increased Risk of Prostate Cancer and Melanoma in Patients with Parkinson Disease

A study that used a Utah genealogic database and the Utah Cancer Registry to examine the relationship between Parkinson disease and cancer suggests an increased risk of prostate cancer and melanoma in patients with Parkinson disease and their relatives.

According to a report published Online…

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Added by Peter Hofland, PhD on September 5, 2012 at 4:00pm — No Comments

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