Earlier today, Abbott, Janssen Biotech and Pharmacyclics announced that they will collaborate in the development of a molecular companion diagnostic test to identify patients with a genetic subtype of chronic lymphocytic leukemia (CLL), the most common form of adult leukemia.

The new companion test will be based on Abbott's proprietary fluorescence in situ hybridization (FISH) technology. With the FISH technology,…

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Earlier today, the Texas Children's Cancer Center announced a new, first of its kind, Childhood Cancer Prevention and Screening Clinic which will screen and follow children who are at an elevated risk for developing childhood cancer.

The new clinic will reassure families of children with genetic conditions such as Li-Fraumeni syndrome and Beckwith-Wiedemann syndrome which predispose individuals to…

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A study published in the January 20 advance online edition of the scientific journal Nature Geneticsfinds new genetic defects in high-risk childhood leukemia subtypes with chromosomal loss.[1] This research confirms evidence that some patients have an inherited cancer syndrome

The researchers, led by St. Jude Children’s Research Hospital scientists, identified a possible lead in…

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A study published in the January 20 advance online edition of the scientific journal Nature Geneticsfinds new genetic defects in high-risk childhood leukemia subtypes with chromosomal loss.[1] This research confirms evidence that some patients have an inherited cancer syndrome

The researchers, led by St. Jude Children’s Research Hospital scientists, identified a possible lead in…

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Whole genome sequencing — spelling out all 3 billion letters in the human genome — “is an obvious and powerful method for advancing our understanding of pancreatic cancer,” according to a new study from TGen, Mayo Clinic and Scottsdale Healthcare published today.

The Translational Genomics Research Institute/TGen demonstrated that the use of WGS “represents a compelling solution to obtaining detailed molecular information on tumor biopsies in order to provide guidance for…

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Scientists have begun to reveal the order of the genetic aberrations in individual cancers in a finding they say is key to early diagnosis and personalized medicine.



“We know that each cancer is a collection of genetic malfunctions,” said Raymond Cho, Ph.D., an assistant clinical professor in the department of dermatology at the University of California, San Francisco (UCSF). “We now show it is possible to determine which changes happen earlier and which ones… Continue

Two new studies highlight the power of sequencing cancer patients’ genomes as a diagnostic tool, helping doctors decide the best course of treatment and researchers identify new cancer-susceptibility mutations that can be passed from parent to child.



Both studies, by Washington University School of Medicine researchers at the Siteman Cancer Center, are reported April 20 in the… Continue

Cancer survival rates could improve soon with whole-genome sequencing, according to two studies published in the April 20, 2011, issue of the Journal of the American Medical Association that describe the first clinical applications of the high-tech process in patients with cancer.



The papers are remarkable examples of the power that genomic data hold for patients with a cancer diagnosis, according to an accompanying editorial by Boris Pasche, M.D., deputy… Continue