Researchers at the Translational Genomics Research Institute (TGen) have begun to identify mutations and cellular pathway changes that lead to lung cancer in never-smokers — a first step in developing potential therapeutic targets. In a study presented at the AACR-IASLC, the Joint Conference on Molecular Origins of Lung Cancer:Biology, Therapy and Personalized Medicine, held January 8-11, 2012 San Diego, CA, researchers confirmed that multiple novel mutations and pathway changes…Continue
Added by Peter Hofland, PhD on January 9, 2012 at 3:30pm — No Comments
As the War on Cancer enters its fifth decade and the number of people being diagnosed with cancer continues to rise, Lung Cancer Alliance (LCA) called for more aggressive integration of advanced imaging technology and biomedical research to improve prevention, earlier detection and treatment of cancer.
"We have developed remarkable new tools for imaging and biomarker identification that can…
Added by Peter Hofland, PhD on January 5, 2012 at 3:30pm — No Comments
A population-based analysis of more than 3,000 families including women with breast cancer, published online October 31, 2011, in the Journal of Clinical Oncology, a tri-monthly peer-reviewed journal of the American Society of Clinical Oncology (ASCO), found that close relatives of women who carry mutations in a BRCA gene – but who themselves do not have such genetic…Continue
Added by Peter Hofland, PhD on October 31, 2011 at 5:30pm — No Comments
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Pediatric cancer researchers at The Children's Hospital of Philadelphia contributed important expertise to a new landmark study of medulloblastoma, a type of brain tumor typically found in children. The large multicenter study defines the genetic landscape of this cancer, and holds intriguing clues to gene changes on signaling pathways that may become fruitful targets for future therapies.
The most common…
Added by Peter Hofland, PhD on December 16, 2010 at 9:30am — No Comments
Lung tumors in those who smoke and those who never smoked have different DNA alterations in the tumor genomes, according to results of a pilot study presented at the Ninth Annual AACR Frontiers in Cancer Prevention Research Conference, held in Philadelphia from November 7-10, 2010.
Based on the results of this study, Kelsie Thu, a Ph.D. candidate at the BC Cancer Agency Research Centre in Vancouver, Canada, suggested that “lung cancer in never-smokers…
Added by Peter Hofland, PhD on November 8, 2010 at 11:30pm — No Comments
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Added by Roxanne Engel, PhD on January 29, 2010 at 5:36pm — No Comments