Peter Hofland, PhD's Blog Posts Tagged 'risk' (47)

Prostate Cancer Deaths Estimated to Grow While Diagnosed New Cases are Expected to Decrease

A new report published today estimates a 5% increase in prostate cancer deaths in 2013 and signal a new trend of fewer men being diagnosed with the disease. Compared to a 15% decrease in prostate cancer deaths in 2012, this year's increase could be attributed to men with aggressive forms of the disease forgoing early detection.

"We must remain vigilant in the fight to end prostate cancer by increasing research funding, raising awareness and education, and continuing to test…

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Added by Peter Hofland, PhD on January 29, 2013 at 7:30pm — No Comments

Test Predicts Presence of BRCA1 and BRCA2 Mutations with High Sensitivity and Specificity, Aiding Clinical Decision Making

About 5% of all breast cancers are attributed to an inherited mutation in one of two cancer susceptibility genes, BRCA1 and BRCA2. Researchers how now developed a new multiple gene expression profile test was able to predict the presence of either BRCA1 or BRCA2 mutations in otherwise healthy women carrying the mutations, according to data published in Cancer Prevention Research, a…

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Added by Peter Hofland, PhD on January 22, 2013 at 6:00pm — No Comments

ESMO 2012 Debate: Is there Enough Evidence to Start Using Aspirin to Reduce the Risk of Colorectal Cancer?

Aspirin, the everyday drug taken by countless people around the world to ward off pain and reduce their risk of developing heart disease, may have a new trick up its sleeve – preventing cancer. A growing body of evidence suggests that taking aspirin may reduce an individual's chances of developing colorectal cancer and perhaps other malignancies, but whether that evidence is strong enough to outweigh the risks of prescribing it to millions of healthy people is the subject of…

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Added by Peter Hofland, PhD on October 1, 2012 at 8:30pm — No Comments

Study Shows Increased Risk of Prostate Cancer and Melanoma in Patients with Parkinson Disease

A study that used a Utah genealogic database and the Utah Cancer Registry to examine the relationship between Parkinson disease and cancer suggests an increased risk of prostate cancer and melanoma in patients with Parkinson disease and their relatives.

According to a report published Online…

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Added by Peter Hofland, PhD on September 5, 2012 at 4:00pm — No Comments

HPV Testing Can Predict Risk of Cervical Cancer for Up to 18 Years

A study published in the online edition of the July 30, 2012 issue of the Journal of Clinical Oncology (JCO) explores the long-term benefits of human papillomavirus (HPV) DNA testing alone, cytology (Pap testing), and combinations of the two, to predict cervical precancerous disease and invasive cervical cancer risk. Based on the outcome, the researchers concluded that primary…

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Added by Peter Hofland, PhD on July 30, 2012 at 9:30pm — No Comments

New Quality Measures to Encourage Better Taking of Family Histories and Referral to Genetic Counseling: Community Oncologists Better at Documenting

Documenting a cancer patient’s family history (CFH) of cancer is important in establishing risk for primary and secondary cancer and identifying individuals who may be candidates for genetic counseling and genetic testing. Prior studies have demonstrated low rates of family history documentation and low referral rates for genetic counseling and genetic testing.



In 2011, the American Society for Clinical Oncology's (…

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Added by Peter Hofland, PhD on June 6, 2012 at 7:00pm — No Comments

Study Shows Relationship Between Weight Loss and Cancer Risk

Postmenopausal women who were overweight or obese and lost at least 5% of their body weight had a measurable reduction in markers of inflammation, according to a study published in the May 1, 2012 edition of Cancer Research, a journal of the American Association for Cancer Research (…

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Added by Peter Hofland, PhD on May 1, 2012 at 11:30am — No Comments

Long-Term Cognitive Effects Study of Breast Cancer Chemotherapy Finds Subtle Impairment Among Women Who Received CMF Regimen

A summary of a study by Dutch investigators published online in the Journal of Clinical Oncology reported that women who received CMF chemotherapy, a combination regimen including the drugs Cyclophosphamide,…

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Added by Peter Hofland, PhD on February 27, 2012 at 5:30pm — No Comments

Early Detection Results in 15 Percent Drop in Prostate Cancer Deaths

While more men are being diagnosed with the prostate cancer, fewer are dying from the disease. Data from the North American Association of Central Cancer Registries and the National Center for Health Statistics, Centers for Disease Control and Prevention (CDC) show that in 2012, incidence rates of prostate cancer will increase slightly, while death rates from the disease will decrease. In 2011, 33,720 men died from the disease,…

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Added by Peter Hofland, PhD on February 7, 2012 at 8:00am — No Comments

Danish Fast Track Cancer Care Program Could Reduce Risk of Recurrence and Lowers Cost to Government

A Danish national fast track system for cancer patients reduced the waiting time between a patient’s initial meeting with a health care provider and their first treatment by four weeks when comparing 2010 to 2002, according to a study presented at the Multidisciplinary Head and Neck Cancer Symposium, held from January 26-28, 2012 in the Biltmore, Phoenix, Arizona.



Denmark’s health care system is state run. Health care services are funded by taxes with no…

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Added by Peter Hofland, PhD on January 26, 2012 at 2:30pm — No Comments

Data From 15 Million Cases in 60 Countries Shows Men at Higher Risk for 32 out of 35 Cancers

While it is well established that men get cancer more than women, and sometimes at considerably higher rates, few scientists have examined why. In an article published this month in the online version of the European Journal of Epidemiology, a group of American and Swedish researchers, including the Cancer Prevention Institute of California (CPIC),…

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Added by Peter Hofland, PhD on January 17, 2012 at 12:30pm — No Comments

Swedisch Study Shows Lower Risk of Breast Cancer Occurrence - But Higher Mortality - Among Low-educated and Immigrant Women

Low-educated and immigrant women run a lower risk of breast cancer occurrence than highly educated women and women born in Sweden. However, the risk of dying from breast cancer is higher for those low-educated and immigrant women that do get the diagnose - a development that has occurred in Sweden during the last ten years. This according to a new study from the Karolinska Institutet based on the records of some 5 million women between 1961 and 2007.…



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Added by Peter Hofland, PhD on January 10, 2012 at 5:30pm — No Comments

Antiestrogen May Decrease Risk for Melanoma, Risk Higher Among Those Not on Therapy

Women with breast cancer who take antiestrogen supplements may be decreasing their risk for melanoma, according to a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research.



Christine Bouchardy, M.D., Ph.D., professor at the University of Geneva and head of the Geneva Cancer Registry, and colleagues analyzed data from 7,360 women who had breast cancer between 1980 and 2005. About half (54%) of these women…

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Added by Peter Hofland, PhD on January 4, 2012 at 3:30pm — No Comments

Antiestrogen May Decrease Risk for Melanoma, Risk Higher Among Those Not on Therapy

Women with breast cancer who take antiestrogen supplements may be decreasing their risk for melanoma, according to a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research.



Christine Bouchardy, M.D., Ph.D., professor at the University of Geneva and head of the Geneva Cancer Registry, and colleagues analyzed data from 7,360 women who had breast cancer between 1980 and 2005. About half (54%) of these women…

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Added by Peter Hofland, PhD on January 4, 2012 at 3:30pm — No Comments

Potential New Use of Denosumab Reviewed at FDA's Oncologic Drugs Advisory Committee Meeting

The U.S. Food and Drug Administration (FDA) has invited Amgen to participate in a meeting of the Oncologic Drugs Advisory Committee (ODAC) on Feb. 8, 2012 to discuss the supplemental Biologics License Application (sBLA) for denosumab (XGEVA®) to treat men with castration-resistant…

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Added by Peter Hofland, PhD on December 29, 2011 at 3:30pm — No Comments

Increased Carbohydrate Intake May Influence Risk for Breast Cancer Recurrence

Polysaccharide starch or amylum is a carbohydrate consisting of a large number of glucose units joined together by glycosidic bonds produced by all green plants as an energy store. It is the most common carbohydrate in the human diet and in staple foods as potatoes, wheat, maize (corn), rice, oats, barley and cassava. Researchers have linked increased starch intake to a greater risk for breast cancer recurrence, according to results presented at the 2011 CTRC-AACR…

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Added by Peter Hofland, PhD on December 8, 2011 at 5:00pm — No Comments

Experts Urge Americans to Rethink Outdated Notions of Physical Activity: Inactivity Increases Cancer Risk

As many as 49,000 cases of breast cancer and 43,000 cases of colon cancer occurring in the U.S. every year are linked to a lack of physical activity, according to estimates presented today at the American Institute for Cancer Research annual conference. The estimate underscores the critical role that both activity and inactivity play in the development of specific cancers.



At the AICR Annual Research…

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Added by Peter Hofland, PhD on November 3, 2011 at 7:00am — No Comments

No Increased Risk of Breast Cancer for Non-Carriers in Families with BRCA Gene Mutation

A population-based analysis of more than 3,000 families including women with breast cancer, published online October 31, 2011, in the Journal of Clinical Oncology, a tri-monthly peer-reviewed journal of the American Society of Clinical Oncology (ASCO), found that close relatives of women who carry mutations in a BRCA gene – but who themselves do not have such genetic…

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Added by Peter Hofland, PhD on October 31, 2011 at 5:30pm — No Comments

Drinking Plenty of Fluids Appears to Reduce Men’s Risk for Bladder Cancer

Drinking plenty of fluids may provide men with some protection against bladder cancer, according to a study presented at the 10th AACR International Conference on Frontiers in Cancer Prevention Research, held in Boston, Massachusetts (USA), Oct. 22-25, 2011.



Although the study did not determine why increased fluid intake might…

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Added by Peter Hofland, PhD on October 24, 2011 at 4:30pm — No Comments

Lower Colorectal Cancer Mortality Rates Associated with Consistent NSAID Use

Postmenopausal women who reported having used nonsteroidal anti-inflammatory drugs for at least 10 years at the time of enrollment in the Women’s Health Initiative study had a lower risk for death from colorectal cancer compared with women who reported no use of these drugs at enrollment, according to data presented at the 10th AACR International Conference on…

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Added by Peter Hofland, PhD on October 23, 2011 at 4:30pm — No Comments

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