Peter Hofland, PhD's Blog – July 2010 Archive (4)

Study Shows: Intensive Chemotherapy May Be Harmful to Most Older Patients With Acute Myeloid Leukemia

The prognosis for nearly three-quarters of elderly patients on intensive chemotherapy for acute myeloid leukemia (AML) is poor, with a median survival of less than six months, according to a study published online today in Blood, the journal of the American Society of Hematology. AML is the most common form of acute leukemia among adults and is a rapidly growing cancer… Continue

Added by Peter Hofland, PhD on July 28, 2010 at 10:00am — No Comments

New ASCO Guideline Update Recommends Aromatase Inhibitors Alone or with Tamoxifen as Adjuvant Therapy for Post-Menopausal Women with Hormone-Receptor Positive Breast Cancer

The American Society of Clinical Oncology (ASCO) today issued a guideline update on the use of adjuvant hormone therapy for women with hormone receptor-positive breast cancer. The Update Committee, convened by ASCO, reviewed evidence compiled through a systematic review of the medical research literature to develop the recommendations. The guideline will be published online today in the… Continue

Added by Peter Hofland, PhD on July 12, 2010 at 9:00am — No Comments

Protein That Predicts Prognosis of Leukemia Patients May Also Be a Therapeutic Target

Researchers at Whitehead Institute and Children's Hospital Boston have identified a protein, called Musashi 2, that is predictive of prognosis in acute myeloid leukemia (AML) and chronic myeloid leukemia (CML) patients.

High levels of Musashi 2 protein is associated with increased cell proliferation, decreased cell maturation, and multiple cancer-related cellular pathways in human leukemias. The protein and the cellular functions it affects could potentially… Continue

Added by Peter Hofland, PhD on July 8, 2010 at 9:30pm — No Comments

Protein Inhibitor Revives Chemotherapy for Ovarian Cancer Patients

Investigators at the Translational Genomics Research Institute (TGen), a Phoenix, Arizona-based non-profit organization dedicated to conducting groundbreaking research, have discovered a way that may help ovarian cancer patients who no longer respond to conventional chemotherapy.

A scientific paper that will be published in the September 2010 issue of the journal Gynecologic Oncology describes how the… Continue

Added by Peter Hofland, PhD on July 8, 2010 at 3:30pm — No Comments