Antineoplaston therapy as treatments for people with cancer is a complementary and alternative medicine (CAM) and is not approved or regocgnized as part of mainstream medicine. The therapy involves using a group of synthetic chemicals called antineoplastons intended to protect the body from disease.

Antineoplastons are made up mostly of peptides and amino acids originally taken from human blood and urine.

Supporters of antineoplaston therapy have claimed antineoplastons are a part of something called the body's natural biochemical defense system. This system is said to act independently of the body's immune system and to protect against diseases like cancer, which involve a breakdown in the information processing of the body's cells.

The supporters claim that antineoplaston therapy has been successful in treating many forms of cancer, even reversing a number of cancers. They claim that people with cancer don't have enough naturally occurring antineoplastons and that this therapy replenishes the body's supply, allowing the biochemical defense system of the body to induce cancer cells to stop growing and to develop features that resemble normal cells (cell differentiation).

Clinical trials
Antineoplastons are currently examined in FDA approved clinical trials. The National Cancer institute and researchers at several cancer centers are also conducting laboratory experiments on the peptides involved in antineoplaston therapy.

Does Antineoplaston Therapy work?
Some patients claim to have been helped by antineoplaston therapy, but these anecdotal reports are not considered evidence of effectiveness by the medical community, either for this or for any other type of therapy. Some promising results for the use of antineoplaston therapy have been reported in small studies.

While many articles have been published and dozens of clinical trials against many types of cancer have been ongoing for several years, there have not been any randomized controlled trials—the type of study that is required for new anticancer drugs to be approved by the FDA and recommended by conventional oncologists.

Bias?
A number of proponents of antineoplaston therapy have suggested that the reviews of this treatment by conventional cancer specialists as biased by their mistrust of alternative therapies. Even some prominent people in the field of CAM have reservations about the effectiveness of antineoplastons. One of these, dr. Andrew Weil said noted that the success rates of this therapy is unknown. “If antineoplaston therapy works, we should have scientific studies showing what percentage of patients treated have survived and for how long, as well as evidence showing how this method stacks up against conventional cancer treatment….Until we have credible scientific evidence showing what antineoplastons are, how they act in the body, and what realistic expectations of treatment with them might be, I see no reason for any cancer patient to take this route."

For more information:
- What are complementary and alternative methods?
- What is Antineoplaston Therapy
- Clinical Trials (gov)
- Complementary and Alternative Methods for Cancer Management

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