Saturday, February 16, 2019

Study Shows How Molecular Profiling may Help Catch Lung Cancer Early, Leading to New Treatments

The world's first genetic sequencing of precancerous lung lesions, referred to as lung carcinoma in situ (CIS) are the preinvasive precursor to squamous cell carcinoma and could pave the way for very early detection and new treatments. A new study published in Nature Medicine by researchers from University College London (UCL) describes the cellular basis of a previously unknown clinical...

Comparison of State-by-State Data Shows Melanoma Survival Varies Regionally

Cancer of the skin is by far the most common of all cancers and while melanoma accounts for only about 1% of all skin cancers, it causes a large majority of skin cancer deaths. According to data from the American Cancer Society, melanoma is more than 20 times more common in whites than in African Americans. Furthermore, the overall, lifetime,...

Study Confirms Complication Rates and Costs for Drugs and Diagnostics Higher in Lung Cancer

According to a new study from The University of Texas MD Anderson Cancer Center, complication rates following invasive diagnostic procedures for lung abnormalities were twice as high in the community setting compared to those reported in lung cancer screening trials. The procedures were also associated downstream average costs ranging from U.S. $ 6,320 to U.S. $ 56,845. In the study,...

Specific Class of Biomarkers May help Take Uncertainty Out of Cancer Prognosis

A cancer diagnosis is a terrifying experience, and for most patients the associated uncertainty is especially frightening. Researchers at Cold Spring Harbor Laboratory in Cold Spring Harbor, New York, have now identified a specific class of biomarkers that may help them predict how how aggressive a patient's cancer will be. "There are undoubtedly dozens or hundreds of mutations that cause...

Childhood Lymphoma Survivors have Elevated Risk of Solid Cancers

With new and advanced treatments, most children treated for various forms of lymphoma have the opportunity to survive into adulthood.  These patients are, however, at risk, for several possible late adverse effects of their cancer treatment. This risk depends on a number of factors, such as the type of lymphoma, the type and doses of treatments, and the child's age...

Despite Receiving Similar Treatment as White Women, Black Women have Worse Breast Cancer Outcomes

Breast cancer is the most common cancer in women in the United States and worldwide. Furthermore, hormone-receptor–positive, axillary node–negative disease accounts for approximately half of all cases of breast cancer in the United States. Undated study results from the Trial Assigning IndividuaLized Options for TReatment or TAILORx study show that even with equivalent treatments in women with hormone receptor-positive,...

The Future of Medicine is Bright: Personalized Medicine, Predictive Analytics and Big Data

Modern medicine is to change dramatically. Over the past 200 years medicine has seen extraordinary developments and advances. From microbiology to the sequencing of the human genome, the advent of CRISPR–Cas genome editing to potentially treat disease and advance drug discovery and development, as well as a better understanding of underlying biology of cancer and hematological disease, and the availability...

Proof-of-Concept Study of Live Tumor Cell Biomarker Test in Prostate Cancer

Results of a risk stratification study designed to demonstrate the ability of a new live tumor cell phenotypic biomarker test to identify patients with low and intermediate grade prostate cancer at risk of aggressive disease, were published in Urology. Prostate cancer is the most common cancer in men in the United States, with an estimated 164,690 news cases diagnosed...

Changing Behaviors: Cigarette Smoking Declines As Vaping Increases in Popularity

Vaping and e-cigarettes have become more popular than tobacco cigarettes with teens. But how does vaping influence trends in smoking? And how does vaping impact trends in smoking and smoking cessation in youths and young adults? A comprehensive analysis, funded in part by the National Cancer Institute, examined the relationship between vaping and smoking among youth and young adults. The...

Colorectal Cancer Screening Helps Avoids Intense Treatments in Men

Colorectal cancer (CRC) is the third most common form of cancer in the world. In Finland, a country with approximately 5.5 million people (compare the United States population in 2017 was 325.70 million), approximately 3,000 new patient cases are diagnosed every year, and roughly 1,200 patients die of the disease. Between 2004 and 2016, an extensive screening program was conducted in...

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