Friday, December 14, 2018

President’s Cancer Panel Identifies Urgent Need to Build on Progress and Increase HPV Vaccination

Each year, human papillomaviruses or HPV causes nearly 630,000 cases of cancer worldwide. The majority of these cancers, roughly 530,000 cases, are cervical cancers, but HPV is also responsible for about 100,000 cancers at five other cancers, including the cancer of oropharynx, anus, penis, vulva, and vagina. HPV also causes genital warts and recurrent respiratory papillomatosis.* The incidence of HPV-associated...

Genetic Profiling may Help Detection and Prevention of Breast Cancer in High-Risk Survivors

Researchers at the St. Jude Children’s Research Hospital in Memphis, Tennessee, found that common genetic variations can help to identify pediatric cancer survivors who are at increased risk for developing breast cancer while relatively young. The researchers found that a combined evaluation of common variants with small effects and rare predisposing mutations among young female childhood cancer survivors may further...

Study Reveals Higher Risks of HPV-Related Cancers in HIV-Infected Hispanic Adults

A study published in the online edition of CANCER, a peer-reviewed journal of the American Cancer Society, shows that Hispanic adults infected with human immunodeficiency virus (HIV) in the United States are at a higher risk of developing cancers caused by the human papillomavirus (HPV) than Hispanics from the general population. The study's findings highlight the need for continued efforts...

Brigatinib Reduces Risk of Progression by 73% in NSCLC Patients with Brain Metastases

Data from the Phase III ALTA-1L trial (ALK in Lung Cancer Trial of BrigAtinib in 1st Line; NCT02737501) showed improved intracranial progression-free survival (PFS) and intracranial objective response rate (ORR) with brigatinib (Alunbrig®; Takeda Oncology) compared to crizotinib (Xalkori®; Pfizer/EMD Serono) among anaplastic lymphoma kinase-positive (ALK+) non-small cell lung cancer (NSCLC) patients. Data for these secondary endpoints was presented in...

Novel Statistical Method Estimates Time to Metastasis of Breast Cancer

A study sponsored by the National Cancer Institute and published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research (AACR), found that while women diagnosed with HR-positive breast cancer have lower risk of progression to metastatic disease soon after the diagnosis, their risk persists for several years. In contrast, the study shows, for...

Aggressive Tobacco Control Programs Reduces California Lung Cancer Deaths by 28%

California has reduced smoking faster than any other state in the Unites States. Early adoption of tobacco control efforts led to fewer people ever smoking, reduced the amount used by those who do smoke and helped smokers quit at a younger age — when their risk of developing lung cancer is lowest. As a result, the authors of a new...

Lung Cancer Mortality Rates Among Women Projected to Increase

The global age-standardized lung cancer mortality rate among women is projected to increase by 43% from 2015 to 2030. This is the conclusion from a recent analysis of data from 52 countries reported in Cancer Research, a peer-reviewed scientific journal published by the American Association for Cancer Research (AACR) covering research on all aspects of cancer and cancer-related biomedical sciences. The...

Analysis Shows Healthy Diets Associated with Lower Cancer Risk

A study published in Cancer Research, a journal of the American Association for Cancer Research (AACR), confirms that a diet that encourages both healthy eating and physical activity and discourages alcohol consumption was associated with a reduced overall cancer risk, as well as lower breast, prostate, and colorectal cancer risks. The study funded by public and governmental grants from agencies...

Immunotherapy’s Promise for Lung Cancer Treatment

Cancer research is often defined by slow, incremental progress, building upon years, often decades, of previous discoveries. Then if we get lucky, someone figures out something that adds jet fuel to the process, propelling the entire field forward with new energy and new optimism. As chief of oncology at Yale and having cared for lung cancer patients for the...

Patients with Diabetes have an Increased Risk of Developing and Dying from Breast and Colon Cancer

Diabetes and cancer are common diseases with tremendous impact on health and healthcare worldwide expenditure. A growing number of epidemiological and clinical studies find evidence suggesting that diabetes is directly linked to an increased risk of developing certain types of cancer. Now, researchers in The Netherlands have performed a unique meta-analysis that excludes all other causes of death and...

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